CafÃ©–au–lait spots are smooth, often irregular, brown spots on the skin. Even though the spots are harmless themselves, they are usually the earliest sign for neurofibromatosis. The color of the lesions (light brown to dark brown) is the reason of its name, which mean â€œcoffee with milkâ€ in French.
Define cafÃ© au lait spots typical of neurofibromatosis type 1 (NF1) and. Their color varies from light to dark brown, and the border may be smooth or irregular.
Six or more cafe–au–lait spots measuring at least 5 mm before puberty or 15 mm after. Usually this means late childhood, around age 7-10, or even not until .